… mode in controlling HuR binding to target mRNA, we aimed to directly compare the in vitro
RNA binding affinity of wild-type HuR and different single-site phosphomimetic HuR proteins …

… protein kinase C (PKC) inhibitors and small interfering RNA … an overexpression and subsequent
RNA binding of HuR have been … This provides evidence that PKCα among the four PKC …

… by different signalling pathways provides routes to functional … after activation of PKC (protein
kinase C) with bryostatin and … 221 is mutated to a phosphomimetic aspartate residue, HuR …

… efforts to dissect the different states of the kinase-substrate … catalytic states of the PKC-substrate
interaction. Specifically, … Hence, a phosphomimetic version of peptide number 14 was …

… Moreover, caspase-2 is a target of alternative splicing which gives rise to two proteins with …
activity. Our previous finding that protein kinase C (PKC) triggered phosphorylation of different …

… In this work, we identified PKCδ as a key player in HuR … ), and anti-PKCδ immunoprecipitate
(PKC) were analyzed by … affects HuR mRNA binding, allowing the association of HuR …

… this work are from W244 to K326 in reference to the HuR FL … to Protein Kinase C δ (PKCδ)
to become phosphorylated. … The assignment of the NMR spectrum of S318D allowed us to …

… Full-length HuR with mutations that affect RRM3 RNA binding … role of RRM3 in RNA binding
and functional activity of HuR. … ), we propose that dimerization enables recognition of tandem …

… As PKC-δ and IKKβ-induced phosphorylation of TTP can … by protein kinase A (PKA) and
glycogen synthase kinase 3 … alterations in HuR translocation and ARE mRNA binding affinity are …

… metalloproteinase-9 mRNA expression and activity in NIH3T3 cells … HuR localization 25 .
Besides, researchers have proved that AMP-activated kinase, JNK, ERK, protein kinase C (PKC…